ATLANTA — Rookie Ronald Acuna Jr. hit two home runs, one of them to lead off the game on the first pitch, sending the Atlanta Braves to a 10-6 win over the visiting Miami Marlins Tuesday.

Acuna hit a leadoff home run for the third straight game, and he became the youngest player in baseball history to go deep in five consecutive games. The Venezuelan phenom was 3-for-5 with four RBIs. He has 19 homers in his rookie season, including eight in his past eight games.

Acuna, 20 years, 239 days old, already had become the youngest player ever to homer four games in a row, accomplishing that feat when he blasted long balls to open both ends of a Monday doubleheader against the Marlins.

The Braves have won four in a row. They improved to 11-3 against Miami and 39-19 against the National League East, which Atlanta leads by two games over the second-place Philadelphia Phillies.

Red Sox 2, Phillies 1: Brock Holt, pinch-hitting for right-hander Rick Porcello, made the starting pitcher a winner by hitting the tiebreaking home run in the eighth inning as visiting Boston beat Philadelphia in the opener of a two-game interleague series.

The scorching Red Sox have won five in a row and 11 of 12. Boston is on pace for 115 wins, one shy of the single-season record shared by the 1906 Chicago Cubs and 2001 Seattle Mariners.

Philadelphia has lost four of five. The Phillies fell into sole possession of the second wild card in the NL, one game behind the Milwaukee Brewers.

Cardinals 6, Nationals 4: Kolten Wong homered and had three RBIs to back the solid pitching of John Gant, who also hit a home run for his first career hit, as St. Louis handled visiting Washington at Busch Stadium.

The victory was the seventh in a row and ninth in the last 10 games for the Cardinals, who are now a season-best 10 games over .500. St. Louis has scored six or more runs in its past six games.

Meanwhile, stumbling Washington has lost three straight and four of its past five games and have fallen back to .500.

Rockies 5, Astros 1: Nolan Arenado clubbed his 30th home run, and visiting Colorado extended its winning streak to four games with a victory at Houston.

Arenado, starting as the designated hitter because of his sore right shoulder, drilled a 96 mph fastball from Justin Verlander (11-8) the opposite way to right field with one on and two outs in the sixth inning. The struggling Astros had claimed a 1-0 lead a half-inning earlier only to surrender it in short order and extend their home losing skid to nine games.

Colorado improved to 12-5 on the season in interleague play.

Blue Jays 6, Royals 5: Kevin Pillar hit a two-run home run with two outs in the eighth inning and had three RBIs to help Toronto come back for a win at Kansas City, Mo.

Indians 8, Reds 1: Corey Kluber cruised to his major league co-leading 15th victory and Jose Ramirez hit his 36th homer as Cleveland rolled past host Cincinnati.

Yankees 4, Rays 1: J.A. Happ allowed a career-low one hit in seven scoreless innings and won his third consecutive start as host New York recorded a victory over Tampa Bay.

White Sox 6, Tigers 3: Jose Abreu drove in two runs, Ryan LaMarre hit his first major league homer, and Chicago won at Detroit.

Giants 2, Dodgers 1: Alen Hanson drove in two runs, including the go-ahead tally on a ninth-inning single as San Francisco pulled off a brawl-marred victory over host Los Angeles.

A’s 3, Mariners 2: Jed Lowrie broke a third-inning tie with a two-run home run, and Oakland held on for victory over visiting Seattle in a game that saw the return of Seattle’s Robinson Cano and the loss starting pitcher James Paxton.

Orioles 6, Mets 3: Chris Davis hit a tiebreaking solo homer in the seventh inning, and Tim Beckham added a two-run shot in eighth as Baltimore defeated visiting New York in the opener of a two-game series.

Diamondbacks 6, Rangers 4: Paul Goldschmidt and Alex Avila homered, and Patrick Corbin gave Arizona its National League-best third double-digit winner by beating host Texas to split a two-game interleague series.

Angels 7, Padres 3: Former Padre Justin Upton homered for the second straight night and drove in three runs while Eric Young Jr. added two RBIs as visiting Los Angeles defeated San Diego.

Brewers 7, Cubs 0: Ryan Braun hit a pair of two-run home runs and Jhoulys Chacin pitched seven shutout innings to pick up his 12th win of the year as Milwaukee won at Chicago.